| In
a research led by investigators at Memorial Sloan-Kettering Cancer
Center in New York, in collaboration with scientists at the Riken
Institute in Kobe, Japan, researchers showed that therapeutic cloning
or somatic cell nuclear transfer (SCNT) has been successfully used
to treat Parkinson's disease in a mouse model. The scientists used
skin cells from the tails of the mice, and then transferred their
chromosomes into mouse eggs stripped of their nuclei to create embryos.
The researchers extracted embryonic stem cells from these cloned embryos.
These cells were coaxed to generate customized or autologous dopamine-secreting
neurons (the missing neurons in Parkinson's disease) and transplanted
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into mice with symptoms
of Parkinson's. The mice that received neurons derived from individually
matched stem cell lines exhibited neurological improvement, but
when these neurons were grafted into mice that didn't genetically
match the transplanted cells, the cells did not survive well and
the mice did not recover.
More to read about this
topic at:
www.medicalnewstoday.com/articles/104431.php
Also, you may go to:
www.newscientist.com/article/dn13523-therapeutic-cloning-used-to-treat-brain-disease
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